Term paper that present the knowledge and depth you obtained in this Essay

Term paper that present the knowledge and depth you obtained in this class. The paper lav be from any topic discussed or not in - Essay ExampleDefinition Cushings Syndrome is a disorder involving the hormones and is particularly caused by an abnormal increase in the amount of the hormone hydrocortisone or other glucocorticoid hormones in the blood (Nieman et al., 2008). In the case of an overactive immune system, glucocorticoids usually deliberate down the inflammation system as a sort of negative feedback mechanism. However, if there is too such(prenominal) production of glucocorticoids, especially hydrocortisone, in the blood, then the entire immune system might be saturnine down, thus leading to a variety of numerous physiological disturbances known as Cushings syndrome (Nieman et al., 2008). Causes The important cause of Cushings syndrome is the overproduction of adenocorticotropic hormone, or ACTH, by the pituitary gland, which is usually known as Cushings Disease. Anothe r cause is an adrenal gland tumor that usually occurs among women over 40 years of age. A third cause is a tumor somewhere in the body which either produces too much(prenominal) cortisol or causes its production, such as tumors in the pancreas, lungs or thyroid that oversecrete ACTH (Nieman et al., 2008). ... However, the most initial step for Cushings syndrome is the ACTH stimulating the adrenal glands for the production of cortisol (Blevins, 2002). Symptoms Cushings Syndrome is characterized by florid purple striae, plethora, proximal muscle weakness, bruising with no obvious trauma, as well as unexplained osteoporosis (Nieman et al., 2008). Other symptoms of the disease involve obesity, depression, diabetes, hypertension, or menstrual irregularity (Nieman et al., 2008). If Cushings Syndrome affects the higher brain centers in the case of complications, it may cause anxiety disorder, obsessive-compulsive disorder, depression, alcoholism and diabetes. Other more noticeable sympt oms include obesity of the upper torso coupled with disproportionately thin limbs, a round and red bet with characterized fullness, and acne or certain other skin infections. The less common symptoms include a buffalo hump, backache, warmth and pain of the bones, rib and spine fractures, weak muscles, excessive hair growth in the woman, impotence and deprivation of sexual desire in men, and certain headache, tiredness and feelings of thirst and hunger (Nieman et al., 2008). Treatment The treatment of prize is surgical removal of the tumor. This should be followed by treatment with hydrocortisone or hydrocortisone replacement therapy because cortisol levels will go down fast once the tumor is removed. Moreover, in the case of patients with malignant adrenal cortical neoplasm, the treatment of choice must be open adrenalectomy (Thomson et al., 2010). Through an MRI scan, cases of mediastinal pack that intertwine with the heart nerves must be done with extreme care so as not to in jure such a delicate organ. Moreover, CT-guided coaxial core biopsy to investigate whether it is